INFLUENCE OF PATERNAL AGE IN SCHIZOPHRENIA
نویسندگان
چکیده
منابع مشابه
Telomere length, family history, and paternal age in schizophrenia
Leukocyte telomere length (LTL) is longer in association with advanced paternal age, but this association has not been examined along with family history (FH) in schizophrenia. LTL was measured by PCR and compared across cases and controls as part of a study to examine the characteristics of paternal age related schizophrenia. The 53 schizophrenia cases had similar mean LTL as 20 controls, alth...
متن کاملAdvancing paternal age and the risk of schizophrenia.
BACKGROUND A major source of new mutations in humans is the male germ line, with mutation rates monotonically increasing as father's age at conception advances, possibly because of accumulating replication errors in spermatogonial cell lines. METHOD We investigated whether the risk of schizophrenia was associated with advancing paternal age in a population-based birth cohort of 87 907 individ...
متن کاملAdvancing paternal age and schizophrenia: the impact of delayed fatherhood.
OBJECTIVE It is well known that advancing paternal age is associated with an increased risk of schizophrenia in offspring, but the mechanism behind this association remains unknown. This study investigates if delayed fatherhood rather than advancing paternal age per se might explain the increased risk of schizophrenia in offspring associated with advancing paternal age. METHODS This is a regi...
متن کاملPaternal age and schizophrenia: a population based cohort study.
OBJECTIVE To investigate the association of paternal age at conception with the risk of offspring developing schizophrenia. DESIGN A population based cohort study. SETTING Sweden. SUBJECTS 754,330 people born in Sweden between 1973 and 1980 and still alive and resident in Sweden at age 16 years. MAIN OUTCOME MEASURES Hospital admission with schizophrenia or non-schizophrenic, non-affect...
متن کاملInfluence of paternal age on the risk of spontaneous abortion.
The frequency of chromosomal anomalies in spermatozoa appears to increase with male age. Because these anomalies play a role in the etiology of spontaneous abortion, an influence of paternal age on risk of spontaneous abortion is plausible but not established. The aim was to characterize this influence in a prospective study among 5,121 California women, who as members of a prepaid health plan ...
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ژورنال
عنوان ژورنال: Schizophrenia Research
سال: 2010
ISSN: 0920-9964
DOI: 10.1016/j.schres.2010.02.791